| High-Fat Diets Linked to Stage III Colon Cancer Recurrence |
BOSTON, Aug. 14 2007 - After curative surgery and adjuvant chemotherapy for stage III colon cancer, patients who ate a high-fat diet were more likely to have a recurrence than those who ate a so-called prudent diet, found researchers here.
Those with a higher recurrence risk ate more meat, fat, French fries, refined grains, and desserts. Jeffrey A. Meyerhardt, M.D., M.P.H., of the Dana-Farber Cancer Institute, and colleagues, reported in the Aug. 15 issue of the Journal of the American Medical Association.
Action Points
- Explain to interested patients that for colon cancer patients treated by curative surgery and chemotherapy, a Western dietary pattern (high in meat, fat, French fries, refined grains, sweets, and desserts) was associated with a higher risk of a cancer recurrence and death.
- Point out that in contrast to the Western dietary pattern, the prudent dietary pattern (high in fruits, vegetables, chicken, and fish) was not significantly related to patient outcome.
- Note that because this was an observational study, causality cannot and should not be drawn from these data.
- By contrast, a "prudent diet," high in fruits, vegetables, poultry, and fish, had no effect on cancer recurrence or death.
The findings came from a prospective observational study of 1,009 patients with stage III disease enrolled in a randomized adjuvant chemotherapy trial from April 1999 through May 2001 |
| Jeffrey A. Meyerhardt, M.D., M.P.H - |
Aug-15-2007:07 54 |
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